With both players aiming to make a statement at the annual claycourt tournament, Kevin Anderson and Raven Klaasen got their campaigns off to positive starts at the French Open on Tuesday.
Anderson received little resistance from 36-year-old Italian Paolo Lorenzi, coasting through the first round with a 6-1 6-2 6-4 victory.
The No 6 seed set up a second-round clash against Uruguayan player Pablo Cuevas.
Having reached the fourth round at Roland Garros for the third time last season, Anderson retired injured during his last 16 match against Croatian player Marin Cilic, and he was hoping to take another leap forward in his flourishing career by progressing to the last eight.
In the opening round of the doubles competition, Klaasen and Michael Venus of New Zealand, the No 10 seeds, cruised past the French duo of Corentin Denolly and Alexandre Muller, who had received a wild card entry into the main draw.
Though Klaasen had progressed to the quarter-finals or beyond at all three of the other Grand Slam tournaments, he was looking to make it past the second round at Roland Garros for the first time.
Venus, meanwhile, was aiming to defend his title after lifting the doubles crown last year with former partner Ryan Harrison of the United States.
They were due to meet the French pairing of Jonathan Eysseric and Hugo Nys in the next round.
South African prospect Lloyd Harris had turned out in the qualifying rounds of the prestigious tournament last week, but he was eliminated in his first match, missing out on a place in the main draw.